Quick Take: The TH-PX500U series is the step up from the Panasonic TH-PX50U series. While we haven't reviewed the PX500U series, we have reviewed the TH-42PX50U, which should deliver very similar performance to both of these models. In addition to slightly different cosmetics, the PX500U series offers some distinguishing refinements not found in the baseline models, including picture-in-picture, a VGA-style PC input, a front-panel A/V input, a built-in TV Guide On-Screen EPG, and an SD memory card slot. The 42-inch TH-42PX500U ($3,500) and the 50-inch TH-50PX500U ($4,500) are currently available.