The channel, EUTube, contains video content ranging from documentaries covering the EU's activities and history to interviews with European commissioners.
Issues such as climate change, energy and immigration will all be covered by the content available on the channel.
Margot Wallström, the Commission's vice president for institutional relations and communication strategy, said the channel demonstrates that the Commission is committed toto citizens.
She added that--particularly the use of video-sharing sites--because it is important to communicate with citizens using all available means.
At present, there are about 50 video clips available on EUTube, including an interview with Wallström, along with a documentary on the EU's postwar development.
The majority of content is in English, with some in French and German, and other languages to be added at a later date.
Tim Ferguson of Silicon.com reported from London.