There's a reason I don't call mirrorless cameras "compact system cameras"--because of models like this, which are compact only when compared to even larger dSLRs. Still it's smaller than a woman's hand and comfortable to hold.
The lenses have a great mix of old and new. For instance, they incorporate a manual aperture ring, but instead of sticking with full stop increments, they embrace the new world of third-stop adjustments. They're not indicated on the lens barrel, but you can distinctly feel them as you rorate the ring.
As with the X100, this lever on the front, which falls under your right forefinger, lets you flip between the optical and electronic viewfinders. When you hold it for couple of seconds, you can actually see the viewfinder's magnifying lens slide into place.
Fujifilm replaced the cheap-feeling navigation wheel of the X100 with four-way navigation buttons. Though one of them doubles as a macro mode switch, the other three have no other function. The Q button brings up a new screen for changing frequently used settings.
Fujifilm has updated the interface for more streamlined shooting. That includes a way to quickly access the frequently used shooting settings, in an interface that's become common among midrange digital cameras.