Of the 30,000 or so laptops in the department's inventory, 1,137 were missing, and of these, 249 contained personally identifiable information, according to a statement on Thursday.
The department said it was "not aware of any data being improperly accessed or used" and noted that access passwords, complex database software and encryption technology limit the potential for misuse of such information.
However, a separate review found 297 cases since 2003 in which, involving 217 laptops, 15 handheld devices, 46 USB flash drives and documents or other materials, the statement said.
In June, the Department of Defense revealed that personal information on about 2.2 million active-duty, National Guard and Reserve troops was stolen from a government employee's house.
That followed the, according to the Department of Veterans Affairs.