This is HI-SEAS, Hawaii Space Exploration Analog and Simulation, a white dome situated on the top of Mauna Loa on the Big Island of Hawaii. It's used to help prepare would-be astronauts for life on the moon or Mars.
A view of the workstations on the ground floor. They're used by astronauts to log experiments or communicate with the outside world and Mission Control. Messages are generally delayed anywhere from a few seconds to over 20 minutes to simulate the actual delay from the moon or Mars.