Warner Bros put up a total of 113 episodes of "Friends," the science-fiction series "Babylon 5," the animated classics "The Jetsons" and "The Flintstones," as well as skits from "MADtv" and an unaired pilot called "Aquaman" by the writers of "Smallville."
Downloads cost $1.99 per episode, and can be viewed on a computer or video iPod.
Warner Bros., owned by Time Warner, said the move to iTunes was aimed at making its vast library of TV shows.
The studio is the latest to joinas growth in DVD sales and television viewership stall.
Apple's iTunes store now offers a total of more than 150 TV shows available for purchase from the Fox, ABC, NBC, CBS and MTV networks.