The magazine, from February 1984, is the first issue of Macworld. The cover features a picture of Jobs next to three Macintosh computers and an inscription that says "to Matt, steven jobs."
Jobs signed the magazine on May 19, 2006, at the grand opening of the Apple Store on New York's Fifth Avenue, according to RR Auction. This video reportedly shows him signing the autograph.
The auction house says Jobs was known to be a reluctant signer. That could explain the steep prices people are willing to pay for his signature.
"It's an exceptional piece with ironclad photographic provenance," said Bobby Livingston, executive vice president at RR Auction, in a statement.
The auction ran from Dec. 6 through Dec. 13 and featured other Apple-related items, including Jobs' original Apple Computer business card from when he was chairman of the board. That item sold for $6,259. An Apple "Think Different" poster set sold for $2,764.
Other items linked to Jobs have also sold at high prices. Last year, a Newsweek magazine signed by Jobs sold for over $50,000. And in March, a job application filled out by the tech mogul in 1973 sold for $174,757.