Jobs will be joined by Avie Tevanian, Apple's senior vice president of software engineering. On tap is an overview of Apple's software road map, including the first in-depth look at Mac OS X, Apple's next-generation operating system.
"Macintosh has returned as a high volume platform for software developers serving the professional, consumer, and education markets," Jobs said in a statement.
For the first time, the conference will feature special sessions for Adobe Photoshop and QuarkXPress plug-in developers.
The conference is set for May 10-14 at the San Jose Convention Center in San Jose, California.