The trial of former Theranos CEO Elizabeth Holmes has already lost three jurors with several weeks of testimony likely still remaining. Judge Edward Davila released a third juror Friday after she admitted she'd been playing the puzzle game Sudoku during testimony. Two jurors had previously been dismissed for reasons related to financial hardship and religious beliefs, respectively.
Three of five alternate jurors have already been tapped to fill the vacated seats in the jury box in the federal courtroom in San Jose, California.
Holmes is charged with multiple counts of conspiracy and fraud over claims she made about the company's compact blood-testing machine. Investigations revealed the technology had serious problems. In a few short years, Theranos went from being valued at $9 billion to being one of the decade's more notorious Silicon Valley stories.
The past week in the courtroom saw testimony from a former scientist at drug company Pfizer.
Theranos failed to impress Dr. Shane Weber when he was tasked with performing some due diligence on the company and its blood testing technology for the pharmaceutical giant, according to his testimony as reported by The Wall Street Journal.
Weber told the court he spent 50 minutes on the phone with Holmes and then sent a number of follow-up questions to the company.
"(Theranos) provided non-informative, tangential, deflective or evasive answers," Weber wrote in a resulting 2008 report that was discussed during his testimony on Friday.
Pfizer ultimately decided to forgo doing business with Theranos and Holmes.
Holmes' defense attorneys argued in opening statements in September that the failure of the health care startup was due to "technical" shortcomings rather than deception on the part of its disgraced founder. Holmes attorney Lance Wade told jurors that the story of Theranos' remarkable fall was "far more human and real, and oftentimes ... complicated and boring."
"Out of time, out of money, Elizabeth Holmes decided to lie," assistant US attorney Robert Leach told the 12-member jury last month.
Defense attorneys later countered that Theranos investors were well aware of the risks involved in backing the startup.
The courtroom drama has been over three years in the making, with Holmes originally charged in June 2018. The start of the trial was also delayed multiple times by the COVID-19 pandemic and by the birth of Holmes' child on July 10 of this year.
Here's what else to know about one of the biggest trials of the decade so far.
What happened to Holmes and Theranos?
In 2003, Holmes dropped out of Stanford University at 19 to found Theranos with the goal of disrupting the blood-testing industry. The company said it was developing proprietary technology that required gathering a smaller amount of blood than a conventional intravenous draw and was more portable than traditional tests sent off to a lab.
Theranos began to see more mainstream attention in 2013 when it signed up Walgreens and Safeway as potential customers. At one point the startup was valued at more than $9 billion.
Holmes began to appear on the cover of various publications, including Fortune, sometimes drawing comparisons to Steve Jobs for her seeming powers of disruption and a penchant for high-necked black tops.
But the fortunes of both Holmes and Theranos began to change in 2015 when The Wall Street Journal took a deeper look into the company. The Journal reported that only a small portion of tests were being done with the company's testing machine, named Edison, and that many tests were being run on other companies' machines, using diluted blood samples. The accuracy of test results that patients received from Theranos was also called into question.
All this led to the, a settlement with the Securities and Exchange Commission and the permanent shuttering of Theranos shortly thereafter.
A 2019 documentary, a book called Bad Blood: Secrets and Lies in a Silicon Valley Startup by Wall Street Journal reporter John Carreyrou and multiple podcasts about the company's precipitous fall helped bring mainstream attention to the story.
Former Theranos employee and whistleblowerin 2020 about the whole saga.
What is Holmes charged with?
Holmes is formally charged with two counts of conspiracy to commit wire fraud and 10 counts of wire fraud.
"The charges stem from [Holmes'] allegedly deceptive representations about [Theranos] and its medical testing technology," reads a statement from the US district court in Northern California.
Essentially, Holmes is accused of lying to patients about how the company's blood testing worked and how effective the tests were. Some of the charges also relate to Holmes allegedly misleading investors about the internal workings at Theranos and how much revenue the company was expected to generate.
If convicted, Holmes could be sentenced to up to 20 years in prison.
What is Holmes' side of the story?
Though Holmes denied that the allegations made by the Journal's original reporting were true, she's never told her side of the story from that point on in depth.
"This is what happens when you work to change things," Holmes said on CNBC's Mad Money in 2015. "First they think you're crazy, then they fight you, and then all of the sudden you change the world."
The 37-year-old reportedly pursued a book deal to get her story out. The book never materialized, but aabout the Theranos collapse, The Inventor: Out for Blood in Silicon Valley by director Alex Gibney, came out in 2019. It didn't portray Holmes in a flattering light and she didn't cooperate with the filmmakers, so her take on the events of the past half-decade largely remains a mystery.
Holmes' lawyers come from the high-powered Washington firm that defended President Bill Clinton at his impeachment trial. One possibility is they'll argue she was following something like the Silicon Valley "fake it till you make it" ethos and that she always believed in the long-term potential of the company and its technology to eventually deliver on its promises.
According to The Wall Street Journal, Holmes' lawyers have said she may argue that "she believed any alleged misrepresentations were true and accordingly that Theranos was a legitimate business generating value for investors."
There were hints of this defense in opening statements, when Wade referred to the company's technology as "real" and "innovative."
On Aug. 28,could seek to defend herself by alleging she suffered psychological, sexual and emotional abuse at the hands of former Theranos president and onetime boyfriend Ramesh "Sunny" Balwani, and that because of submissiveness to him, she believed allegedly fraudulent statements she made were true.
This strategy was also foreshadowed in opening arguments in which Wade referred to Balwani's temper and promised more related evidence would be presented during the trial.
Lawyers for Balwani called abuse allegations "outrageous." One of the filings, by lawyers for Holmes, said she was likely to testify.
We'll soon see whether Holmes ultimately takes the stand to tell her side of things.
How can I watch the trial?
The trial officially began Sept. 7, with opening arguments the following day. There isn't an online feed of the trial, and television cameras aren't allowed in the courtroom, so the best way to follow the case will be via reporters in the room taking notes the old-fashioned way.
In total, over 200 potential witnesses have been identified between the prosecution and the defense, so it's possible testimony will go on for weeks.
Balwani faces similar charges in a separate trial scheduled for next year.
Both Holmes and Balwani have pleaded not guilty.