You can say, "Alexa, where can I get a COVID vaccine?" to see a list of options in your area. You won't be able to book your appointment through your Amazon Echo smart speaker or your Echo Show smart display, but Alexa will search nearby places on your request and you can call and get info from your Echo device.
Vaccine info is the latest addition to Alexa's coronavirus repertoire. The digital assistant can similarly connect you to places to get a test and can answer questions about vaccine eligibility for more than 85 countries.