Sure, the room and things in it can change audio results. That's a given. I watched a show about replacing the old wood floor at the Boston Symphony and they were very worried about the effect it would have.
As far as booming bass you could adjust the bass level down. As to echo, curtains in the hearing room can help.
My HT has started sounding weird. It has a bit of echo and booming bass. I haven't made any changes to the settings neither have I made any changes in the positions of the speaker or the sub. The only thing that has changed in my room is my window. We replaced my old window and got this bay and bow windows installed. It is right next to my right rear speaker. As you can see in the image, it has a curve inwards. Does it have anything to do with the difference in sound?