I like the advice jpoliakon gave in the Virus forum which is similar to some others:
"Since your machine is stable and is updated with all critical updates, hold off on SP2 until all the bug droppings settle. My advice: Stand on the sideline and watch."
Some long but good reading mainly towards the posts of yesterday/today in the Virus/Scty Forum:
"Microsoft is well aware of how SP2 can affect applications; the software behemoth has already published a list of nearly 50 programs that face problems if the service pack is installed. Microsoft has also had to issue a patch that allows its CRM (customer relationship management) product to continue working once SP2 is installed."
along with those 50 apps that "seem to stop working" once SP2 is installed shown here in MS Knowledge Base (MSKB) http://support.microsoft.com/default.aspx?kbid=842242
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