If you just want the 2-pane view, not to a particular folder, just hold down the Windows key (the "flag") and press "E"
That will open to where your "My Computer" is high-lighted on the left, and expanded on the right.
If you need it to a particular folder, by having a shortcut on your desktop to the folder, then do as Cetin mentioned, except have the name and path of the folder at the tail end of that same command. For example (copied from a working shortcut on my PC):
%SystemRoot%\explorer.exe /n, /e, C:\DownSORT\Amiga
Once you have that specific shortcut on your desktop, then just open the properties, and in the "Shortcut key" field just press the (for example) "G" key. (the CTRL and ALT will be there automatically.)
Then close the properties.
All you need to do then is press CTRL-ALT-G and BINGO! the explorer will open, in folder (2 pane) view, with the desired folder already selected.
Note: Shortcut keys typically only work if the shortcut icon is either on your desktop, or somewhere in your Start and/or Start>AllPrograms path. AND you must not already have that key combination used.