MCE is a weird version. It's closer to XP Pro than home and then you run into the issue of XP, XP SP1, XP SP2 and XP SP3 CDs.
If you have nothing to lose, why not?
I have a gateway all in one running windows xp media center edition. i need to run a reapir because i have corrupt windows files. i dont have the discs that came with the computer and contacted gateway and they cannot get them either. my question is can i use a windows xp home edition disc to repair my OS?? i was told it would work because the only thing a repair does is fix the broken or corrupt file. only differnce between xp home and media center edition is that MCE has windows media center preloaded onto it