The contents of a DVD is read-only. Changing the attribute doesn't change that.
Copy the contents to your hard disk and uncheck the read-only attributes there. Then run from there.
Unable to load X-plane 11 on Windows 10 computer via DVD, read-only box unchecked, starts to load for about 2 seconds, then stops and read-only box has check again. How do I disable read-only attribute?