Hello. I am in the same boat with the black Friday special. Here are the settings that I have found to be the best. It is a combination of a basic THX optimizer, personal preference, and researching calibration settings for similar televisions. I have not messed with any of the professional settings though, but am keeping an eye out if anybody posts anything.

Custom 1
Auto Brightness Off
Backlight 40
Brightness 45
Contrast 80
Color 50
Tint 0
Sharpness 50

Advanced Picture
Color Temp Computer (seemed like a happy medium between warm & cool which were either too red or too blue)
Black detail Off
Reduced Signal Noise Off
Reduce Block Noise Off
Film Mode Auto
Picture Normal

I have always read that it is best to turn most of the televisions "extra" features off, as mentioned above, because the tv is adding unnecessary extra processing to the image and alters the way the original picture was intended to look.

Hope this helps and if you stumble across any other info, please keep me posted.