Try a generic reset.
Unplug everything from the PC desktop. EVERYTHING. Press and hold the power button for one minute, release and then plug in ONLY what's needed.
See if it comes back.
Good afternoon, everyone. I'm having some issues with my USB ports not functioning. The issue began after I turned off my desktop in order to install a new memory card. After I installed the memory card and reconnected everything I went ahead and turned on my desktop as usual this is when I noticed my mouse and keyboard weren't functioning. I've turned off my PC for several minutes, left it on for several minutes and tried all 12 USB ports and not a single one is working. At this point I'm not sure what else I could do as every other remedy I've found online involves actually being able to use my keyboard and mouse.
If anybody has any suggestions I'd really appreciate it.