There are alot of well intentioned posts here, but all you really need to do is save any files that you personally created. ie word docs or any other "office" files. Since you are running vista most everything else should work ok.
As everyone here has said a clean install is always best with windows, but if you are really worried at least check toshiba's web site about the upgrade.
I have been upgrading my computers since windows 98 came out and believe me vista > win7 is the easiest yet.
No matter what , you will be very happy once you complete the change. win7 is so smaooth compared to vista.
good luck

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