The simple answer is no.
But I have Windows 2000 on many machines at the office and no plans to change them to XP. We have XP as well and see no benefit (for the office) to move to all XP.
My advice? Move away from Windows ME, stick with 2000.
I have two computers with windows software: one ME and one 2000. I would like to upgrade both to Windows XP Home. Can I do this by buying ONE XP Upgrade and then install it on both computers?