You didn't tell us which operating system you're using and although you mentioned Ad-Aware and Spybot, you didn't list their versions and whether they are up to date..Both those items would sure help...
Assuming both Ad-Aware and Spybot are up to date, please try the following steps.
First, download, install, and update the free Ewido program from the link below:
Ewido Security Suite
Once that's done, then restart the computer into "Safe Mode", using the instructions below, then while in "Safe Mode", run a full system scan with Ewido, Ad-Aware and Spybot, plus your onboard antivirus program.
How To Start In 'Safe Mode'
Hope this helps and let us know how it goes.
It appears I've encounted some spyware that nothing can eliminate. Pray that you don't come across it. Not even Adaware or Spybot can fix this one
It starts when I sign on to the Net. I'll check to see if my pop up blocker (YAHOO) is on. It is, but I'll check a few seconds later and it has been shut off for some reason, even though I always maintain it as ON in my SECURITY folder.
Next a small black box pops up warning me that spyware may be slowing down my PC. It asks me to click OK if I want to SCAN for problems but I never have. It appears to be an advertisement. I close by clicking the X and move on.
The next thing I notice are 3 new bookmarks and also some folder icons placed on my desktop. They are always the same ones....ADVANCE YOUR CAREER, FIND YOUR NEW DREAM DATE, GUARANTEED APPROVAL,YOU'RE APPROVED, CASINO GAMES, GET OUT OF DEBT, MEET SOMEONE SPECIAL. I've never visted any of these sites and no one but myself has access to my PC.
Unless someone out there has a suggestion, I'll probably be stuck with this trash mail for as long as I keep my computer. Sorry for the long post but I tried to not leave anything out.