Microsoft Works by going to the Control Panel, add/remove programs and un-install it.
The only problems you'll have is if you have and documents that you created using it. I personally don't like using it. I'd prefer Open Office(FREE version of Microsoft Office) and Microsoft Office, but these programs will NOT open the .wps documents. So before you remove it, please make sure to download and install Open Office or Microsoft Office, open the Woeks document, select all copy and paste the document to a Word or Text document and save it.
Open Office can be downloaded from here.
I'd like to uninstall Microsoft Works 8 from my laptop and not sure if it will cause problems or if it will even let me. I have Vista.