from Carol's post in the link below;
http://forums.cnet.com/7723-6132_102-529651/opera-crashing-constantly-also-mirar-issue/?messageId=5147257#message5147257
If you cannot get any of those RKills to work, reboot the computer into it's Safe Mode and run RKill from there. Then, without rebooting run MBAM and SAS.
You may have to repeat this process more than once until you can boot into Normal Mode and run RKill from there.
Mark
I have a trojan in my registry. It will not let me download and open anything that can get in and scan. I have tried Rkill, but will not let me run scan, not even online scan. Help!!! I have run a portable version of Superantispyware and it finds one virus call HKCR\.exe. and says it removes it, but when I immediately scan again, its still there.

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