it is possible. BleepingComputer has a great tutorial for it. Please follow it exactly.
http://www.bleepingcomputer.com/forums/How_to_remove_SpySheriff_Winstallexe_Spysheriffexe-t22402.html
My notebook (using window XP) is infected with spysheriff. The program has not completely finishing running yet (I hit the pause option).
I did some research online and most of the postings requires that I download at least 4 different programs to route out Spysheriff. Problem is - it has not finished running and my notebook in incredibly slow and I cannot open up internet explorer let alone download the needed spyware removal programs.
Can i remove spysheriff without letting it run its complete cycle?
Thanks.

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic