What the exact model number and firmware that you have?
Very frustrating problem with the combination of a Samsung BD-P1600A and the recently released Iron Man 2 Blu-ray.
The player has the latest firmware (August 2010).
The problem is the sound and the video going out of sync. To get the video and sound back in sync it is necessary to pause and then resume. The problem appears to happen after any really big subwoofer action. This happened at least 10 times during the movie's 2hr duration.