a "sticky" post that you should read through for some of the most recommended utilities for cleaning up the computer. This is the link -
You will see Malwarebytes listes as well as Super Anti-Spyware and I believe Hitman Pro is also listed (if not get and use it anyway).
If you can boot the computer something that will help is to open the Task Manager and kill off processes associated with the various malware.
Once you have used the various malware removal and virus removal utilities you should also make use of Windows Uninstall applet in the Control Panel to remove programs you do not recognize as being necessary to you.
I got a computer that someone was trying to get rid of for like $20. It looks half decent but they told me it has viruses on it. When i started it up, i could see the limewire icon on the desktop. The background screen automatically changes on startup to a screen that says click here to remove spyware and there are constantly things popping up in the bottom corner saying your computer is infected. So it is pretty bad. I would just format the computer but i dont have a windows cd so id be screwed. Whats the best way to clean this computer? I dont care about anything on it.