And I'm going with no. Most folk should stay out of the registry.
Did you try McAfee's cleanup and removal tool?
I need to install a software. It seems to use the same register as MCafee Virus Scanner. ("unable to write inside TEMP variable path"). After uninstalling the Virus Scan, the register <span id="INSERTION_MARKER">{B54F3741-5B07-11cf-A4B0-00AA004A55E8} (with data c:\program files\mcafee\virusscan\scriptcl.dll) is still there. The register should be erased during the uninstallation process, shouldn't it? Is it safe to delete the register manually?

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