Often ports such as SATA, memory, PCI-E that have not been used recently (or ever-especially 3 years); tend to build up with dust, if you haven't used a port for some time, blow them out to clear out the dust and debris.
It wouldn't hurt to do a thorough cleaning of all your computer internals on this 3 year-old system.
Also wouldn't hurt to use all new cables for new components, peripherals.