The topic of cache ram in the hard drive is now a well discussed subject. I'm going to give you my answer and hope it makes sense.
-> Perform a benchmark on both drives using your apps as a guide.
Get the drive the got the better score.
I am upgrading from a 80gig IDE hard drive to a SATA 500gig hard drive to do a clean install of win7 X64 home preimun; What is the difference between a SATA 500mb 64cache and a SATA 500mg 32cache?