This would be the Voice guide option. System > Accessibility > Voice Guide, and just turn it off there. This should resolve this for you.
Just got a Samsung series 6 6200 series LED TV and am hoping there is a way to shut off the voice which announces every function you are doing while using the remote. My most pressing issue is the voice that announces the volume number as you adjust it on the television. Please let me know of the way to shut off this feature.