I'm interested in getting a Karma and using it with my Mac so I did some research regarding it's Mac compatibility. It seems that you need to get some free software. The web page with the list of builds of RMML is: https://rmml.dev.java.net/servlets/ProjectDocumentList?folderID=437&expandFolder=437&folderID=0 A direct link to download the latest build on the previous link: https://rmml.dev.java.net/files/documents/1105/7250/rmmlite.jar It is a "Lite" Java version of the Rio Music Manager (RMML) that works on most any platform. I have OS10.39 and the software seemed to start fine on my computer (although it wouldn't let me use it- as there was no Karma hooked up to my network). I'm not sure, but you may have to connect the Karma to the ethernet port of a Mac to get it to function. It may work with USB on a mac with the RMMLite, although it would certainly take a long time to get music onto it if it's not USB 2.0. I hope this info isn't too late and that it helps.