From here you could probably go with most of the components used in this years Dream Machine from Maximum PC
(Personally I would substitute GTX 480's for triple or quad ASUS Ares Radeon HD5870x2 4GB GDDR5 memory)
Now that we're done with the dreaming, what is the real budget and what kind of rig do you want?
I'm building a new gaming rig with a budget of 1,000,000 dollars (yes a million). Any ideas?