If your replacement motherboard is from HP and the same make and model as originally in the system, then no. Otherwise, it's very possible.
hey all..well im gonna have to replace my mobo and psu.one of them went bad, so just replacing them both to to be safe. my comp specs are hp pavilions a340n, pent 4 @2.6 ghz, 512 ram, Intel 82865G graphics controller, xp home sp2,...but yeah.. iv read that oem versions are licensed to one specific computer. so by replacing my mobo em i gonna have a problems with xp, saying that its on a different machine