You can FIX these entries via HJT.
Make sure you can view hidden and system files: Instructions here
Then Boot to safe mode: Instructions here
Have Hijack This fix the following by placing a check in the appropriate boxes and selecting fix checked.
Make sure all browser and all Windows Explorer windows are closed before fixing
ALL the entries like these ones:
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = http://red.clientapps.yahoo.com/customize/.../search/ie.html
Have a look here:
what is http://red.clientapps.yahoo.com/customi...ch/ie.html in my hijackthis log? i use win XP. run ad-aware and spybot weekly.