Most likely not. If it is FAT32, then a DOS boot disk can be used to see it. If DOS can't see it, then its likely you fell into the DRIVE MANAGER, EZDrive or Maxblast trap. People install drive extenders and are unaware of the future implications. One being you can't pick up the drive and install it elsewhere.

Your knowledge of how the drive was prepared is needed to recover the data. Sometimes you can boot the drive and backup. Sometimes you boot up a Maxblast disk and remove the extension.

Best of luck in recovery.