The buttons not working at all indicates a serious issue. If you just purchased it, I would suggest exchanging it.
There are some features (picture control options) that aren't accessible from the menu when you're hooked up through a digital signal. But those would be blanked out in the menu, and not automatcally disable the buttons.
Hope that helps, and keep me posted.
Just received this monitor. Set it up, turned on, all working ok. Updated drivers, then accidentally turned monitor off whilst trying to adjust brightness etc. Monitor would not turn back on - I had to use the switch at the back to turn off and on again. Now NONE of the buttons on the front of the monitor work, although the display works fine. Any suggestions please?
Also does auto adjust not work through DVI (when the buttons work, that is)?