Did the computer come with Vista installed or did you upgrade to it?
It sounds like you need new firmware for the drive.. Samsung should have that which is Vista compatible.
Hope this helps.
Grif
I'm on Vista home premium just in case anyone wonders why I'm posting on the vista forum. When I try to install something from my Samsung Writemaster DVD drive, it says that a file on the disc is corrupt. I've tried with three different drives and different IDE cables too but it happens the same each time. I wondered if a bent pin on the drive could be damaging tha IDE cables. I've also had problems when installing VIsta with this drive when I kept getting Blue Screen errors during installation.

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic