Games take quite a bit of machine preperation to work properly. For instance Swkotor errors at http://support.lucasarts.com/trg/tgd.asp?id=2688&g=148&s=4 may not exactly match your error, but the clues are the same.
Update all drivers for the machine (Windows Update and Driver Update do not work for this!) and then try again.
My son got the Star Wars Knights of the Old Republic PC game. We installed it and when he went to play the game there was and error message: Swkotor has caused error in (unknown) Swkotor will now close. The screen goes into Safe Mode also. We uninstalled and reinstalled the game and it is still the same. What does the error message mean and is there a solution. We are able to play other games on the computer. We have a Dell computer with Windows ME edition. Thanks for any suggestions