Please provide us with more information, including the symptoms (does IE provide an error message, simply not start, display distorted pages, etc), what operating system and version of IE you use, and what you do for malware (particularly spyware) protection. Anything you can tell us will help us diagnose and solve your problem.
Basically for months now my Internet Explorer hasn't been working at all. But my Netscape has been working. How weird is that? What's been going on?