I'm sorry to hear that you're having this issue.
I'd recommend taking the disc out of the tray and then closing it. With the unit still on, press and hold the FF>> button to reset the machine. Let it restart once without a disc in the tray, and then power it down. Try again by inserting the disc.
I upgraded from the 2.08 to the 2.12 firmware on my PD-1600. Now the remote is only good for Power and Open. No other buttons work.
At first the unit recognized Blu-Ray discs, but after a few restarts, it now says No Disc (on the TV) with a BR disc in, although it says LOAD on the player itself.