But there is not enough clues here for me to offer advice.
I will share that my TX did that but I had to find what old Palm software was incompatible. It was not fun and I'll call such "fairly advanced troubleshooting." Your post has so few details that I'm taking a wild guess there was some older Palm unit.
just got a new tungsten e2- we did a hot sync for the first time and all my info migrated into my new handheld- But since then, every time i hot sync i get a fatal error on my handheld and have to reset it. Is there a compatability issue?