Two things come to mind.
First, you neglect to mention how much RAM you have, and what OS... But for XP, 512MB-1GB is what you want, Vista is 2-4GB, preferably dual channel. Windows 2000 is about the same as XP, and Win98/Me can probably get by with just 512MB.
Second, get rid of McAfee VirusScan. Never before have I seen a single program slow a computer down so much that isn't some kind of virus or malware. It is inexcusably bad in that regard, or at least it was the last time I used it about a year or two ago. While it's possible it's improved since then, I highly doubt it. By my estimations, it saps anywhere from 25-33% off the top of your overall system performance, and that's just the resident scanner. Try replacing it with something like AVG Free or Avast.
Other than that, you'll need to provide some more specifics about your system. Some of the things in the red text that's above every new post you make, which reads as follows:
Note: If you're asking for technical help, please be sure to include all your system info, including operating system, model number, and any other specifics related to the problem.
Microsoft Word is taking almost 30 seconds to start after I open it. I would really like to speed up this process, and other applications? Does anyone have any suggestions. Here's a list of what I've tried so far:
Complete scan with McAfee, Spybot, and Avast
Stopped a lot of startup programs and services
Checked for errors and defraged hard drive
Made sure prefetch is enabled (3) in registry
Added " /prefetch:10 " to the target of Word shortcut
It's still loading super slow. Does anyone else have any tips to open AND close applications faster?