1.) If you upgraded from Windows XP, you may be able to log into the 'hidden' administrative account named administrator, with the default password being blank.
2.) Try booting into Safe Mode (press F8 during boot) and see if performance is restored to normal levels. If so, it is an issue with startup items (applications that load automatically when Windows starts) slowing your system down. You can disable these by opening msconfig (press Windows + R and enter msconfig into the Run box), selecting the Startup tab, and unchecking everything that isn't necessary.
3.) You didn't mention which security scanners you used, but just to be on the safe side I would run a single pass with the free version of Malwarebytes Anti-Malware.
4.) Registry cleaners will not help with such issues and frequently only make matters worse. Thus, I would strongly advise against buying one, especially at this point.
5.) Just to clarify, is that Windows Vista 32-bit or 64-bit? (There was a typo in "34-bit.")
Let us know.
John
I have been tossed around like a rag from Microsoft, my computer manufacturer, and my ISP regarding the issues I have and I can't afford to pay Microsoft 60 dollars for one hour of help. About 4 months ago I somehow lost administrator rights so I cannot do updating, look up my updates, I cannot open network,disk clean up, user accounts,disk defragmentation,back up and restore, default programs, and so on. I am only able to get into uninstall programs. My computer is sooooooo super sluggish and I really do not have much installed on it so I know it's not overloaded. I also keep getting Internet Explorer cannot display this page and I click on diagnose connection and get back IE could find anything wrong with your connection. My ISP is through Windstream ( I have heard a lot of people complain about them but I don't know if that may be a part of the problem. When I write to microsoft I get directed to forums and I am totally computer illerate. And I have noticed lately I will see the windows update icon at the bottom of my taskbar but when I try to click on it it just disappears. I have ran multi scans for viruses and only a few tracking cookies could be found. My computer used to fly to a site but now it takes forever to load. I see registry cleaners advertised but I would hate to pay for something that may not work. Anyone ever experienced this type of problem or know what I could possibly do??? HELP ASAP, I do not know where else to turn.One more thing I have Windows Vista 34 bit. Thanks, Shawna Halen

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic