I'd do two things. Reset Chrome (how is on the web) and tell Chrome to stop running in the background.
Click on the Chrome menu (or press Alt+E)
Select Settings
Click on the link titled ‘Show advanced settings‘
Under the section headed ‘System‘ untick the box next to “Continue running background apps when Google Chrome is closed”
I have a desktop computer hooked up to a monitor-- both are new. Windows 10 is fully updated.
When I restart the computer, sticky notes that had been along the edges end up toward the center of the screen. Notifications that should appear on the bottom right also appear towards the center of the screen.
Another issue, which may or may not be connected, is that after restarting my computer, while on lock screen, videos in chrome will start playing. These are videos I've finished-- tabs on Netflix and youtube-- that restart on their own before I even get into the desktop.
I've ran scans on Bitdefender and Malwarebytes, and no issues were found.

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