If so, you may have to call it dead. http://www.rosewill.com/rosewill-rnx-n250pce-wireless-pci-e-n300-wi-fi-adapter.html#product_tabs_Downloads doesn't list Windows 10 so ask about that.
I was using an Edimax USB network card until I decided I would prefer something a little more reliable. I purchased a Rosewill N300 Wireless N PCI-E Adapter RNX-N250PCe from Amazon (using my sister's account, since she is the one with Prime shipping). I was not notified that it was shipped (early, actually), and the package was rained on and left in the sun for a day or two. However, it was a large box with a lot of plastic inside, so I decided to try out the card anyway.
After installing it (leaving it a day or two to make sure it was in no way wet), I have found that it will connect to my router (Arris DG860) and briefly to the Internet, but loses the Internet connection almost immediately (long enough for me to reach beta.speedtest.net, but not long enough to even register anything higher than 0.00 Mbps on the test). After losing the Internet connection, it claims to be connected to my network with no Internet connection. I cannot connect to http://192.168.0.1 while using this new network card, either. I've updated the driver with the most recent version. Is there any way that this is a software issue, or will I have to return it as a hardware issue?