Do you use Windows ME or XP and ran System Restore? If yes, it is known issue. See Error: "Unable to initialize virus scanning engine . . ." after running Windows System Restore or installing Norton AntiVirus 2003/2004
If not, try the other possible solution:
Error: "Auto-Protect Warning: Unable to initialize virus database files" as Windows loads (that is for earlier version of NAV but it is safe to try)
This past weekend when starting up my computer a message on a red background came up saying, "NAV auto-protect unable to initialize the virus scanning engine database files."
All the other applications from my Norton 2003 are runnning fine except this one. I've tried everything I can think of to get this operational. Do I need to re-install the anti-virus software?