I vote no.
http://www.dslreports.com/faq/7571 shows the system requirements, and Mac OS isn't mentioned.
But you can run Windows on your Mac, if you like: http://www.apple.com/macosx/features/bootcamp.html
Just buy a copy of Windows XP! But I'm not sure about the support of that camera.
Can you get MSN messenger on a mac, and use the isight camera with MSN?