If you were using Linux this does work, but not for Windows.
There are some new "Portable Applications" such as Portable Firefox and others that don't require an install but for most people they are thinking office and games which are not portable.
About that firewire connection. Some like it but at the office a few firewire drives (and our customers too) lost all their files. It appears that Windows and firewire is still under development. Connecting the drive via USB 2.0 solved those drive issues. On the Apple however the reverse is true and we connect with firewire.
I've got an external 300gb firewire drive connected to my PC, which has a 160gb internal drive. I'm going to get rid of the PC soon, but it will be a while before I get one to replace it (I'm moving overseas).
What I'd like to do is move all of the programs and data from my internal HD to my external HD so I can still access them with whatever computer I use in the interim (e.g. my girlfriend's notebook PC or computers at work).
Is this possible, and if it is can someone please point me in the direction of how to do it? I don't need step by step instructions, just an idea of how to proceed. Thanks.