Could be a sign of BIOS (outdated?) or motherboard drivers. Be sure to not use the front USB ports in desktops.
-> Your post left out all machine details. There were some 1GB RAM Windows machines on Atom CPUs and they were pretty horrible.
Sometime in the last couple weeks my Logitech M185 mouse (and Microsoft and Verbatim) is lagging/freezing. With their Logitech options software I can see the mouse disconnect. I have reloaded drivers and reinstalled windows and still lags even in Windows 10 safe mode. Help please!