no difference as long as it fits and mounts properly in the case and affords the right number slots for peripherals. You may need to upgrade the RAM if the existing RAM is less than DDR2-667. Keep in mind that MB has only two DIMM slots so if you want or need more RAM, you need to factor that in for the upgrade.

If I were you, I'd look further. The link above shows users aren't real high on that MB.