Most likely: heat. Remove dust from the inside, check all fans. Try with the case open (and if possible use a ventilator to blow cold air in) to see if it makes a difference.
Hi Guys,
Most games that put the PC under heavy load will crash to desktop after 10-20 minutes of playing. I can only avoid the issue by putting the game settings to low.
I've tried a second GPU and had the same issue along with sending my GPU back to the manufacturer and I was told it is fine.
I updated my BIOS and drivers.
GTX 1080
Appreciate any help

Chowhound
Comic Vine
GameFAQs
GameSpot
Giant Bomb
TechRepublic